Skip to main content
. 2022 Jan 21;64(1):3–12. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_104_21

Table 3.

Summary of glia-related genes differentially methylated sites in epigenome-wide association studies in schizophrenia

Author Symbol Gene name Gene annotation CpG site/position SCZ HC Subgroup Tissue Region Ethnic group/race
Wockner et al., 2014[32] SOX10 SRY-box transcription factor 10 5’UTR; Exon 1 cg23109891 and cg06614002 23 24 SCZ FCA United States Undeterminate
ZNF804A Zinc finger protein 804A Body ch. 2.3731798R
Lee and Huang, 2016[33] GNA13 G protein subunit alpha 13 Promoter - 191 335 SCZ DLPFC (BA46/9)A United States Presumably Caucasian
van Eijk et al., 2015[34] HLA-C Major histocompatibility complex, class I, C Intron 4 cg16097079 260 250 SCZ PBCB United States Undeterminate
Kinoshita et al., 2013[35] GFRA2 GDNF family receptor alpha 2 Intron 1 cg22276619 24 23 Medication-free SCZ PBCA Japan Japanese
HDAC4 Histone deacetylase 4 Promoter cg15142485
PCM1 Pericentriolar material 1 cg25884094
CD244 CD244 molecule cg11939496
FAM173A Adenine nucleotide translocase lysine methyltransferase Intron 2 cg09830866
MPG N-methylpurine DNA glycosylase Exon 1 cg16003913
Hannon et al., 2016[36] DDO D-aspartate oxidase Intron 2 cg14038731 414 433 SCZ PBCA United Kingdom Presumably Caucasian
FAM126A Family with sequence similarity 126 member A Promoter region cg10311104
IL15 Interleukin 15 Intron 3 cg11418177
SIK3 SIK family kinase 3 Intron 1 cg23684410
TNFAIP8 TNF alpha induced protein 8 Intron 1 cg03665078

AInfinium humanmethylation450 BeadChip Kit (Illumina); BInfinium humanmethylation27 BeadChip Kit (Illumina). SCZ – Schizophrenia; HC – Healthy controls; DLPFC – Dorsolateral prefrontal cortex; FC – Frontal cortex; PBC – Peripheral blood cells