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. Author manuscript; available in PMC: 2022 Oct 9.
Published in final edited form as: Anal Chim Acta. 2021 Jul 26;1181:338873. doi: 10.1016/j.aca.2021.338873

Figure 6. MS/MS spectra of SAM from A549 cells exposed to 13C6-glucose or 13C1-CH3- methionine.

Figure 6.

Cells were grown as described for Figure 5.
  1. MS/MS of m0 isotopologue of SAM (399.1443 m/z) from an unlabeled sample
  2. MS/MS of m1 isotopologue of SAM (400.1479 m/z) from a 13C1-methionine labeled A549 cell extract,
  3. MS/MS of m5 isotopologue of SAM (404.1613 m/z) from a 13C6-glucose labeled A549 cell extract.

Data were acquired at a setting of 500 K mass resolution with 10 μscan/scan. Asterisks(*) represent 13C.

Dashed arrows represent the fragmentation positions giving rise to the observed m/z.