TABLE 1.
RTOG 0415 target and normal tissue guidelines
| Dose goal (Arm 2) | Minimum PTV dose (encompassing ≥ 98% of PTV) | Minimum CTV dose (encompassing ≥ 100% of CTV) | Maximum dose to PTV (no variation) | Maximum PTV dose to PTV (minor variation) | Maximum PTV dose to PTV (major variation) |
|---|---|---|---|---|---|
| 70 Gy | 70 Gy | 74.9 Gy | 77 Gy | >77 Gy |
| Normal organ limit (Arm 2) | No more than 15% receives dose that exceeds | No more than 25% receives dose that exceeds | No more than 35% receives dose that exceeds | No more than 50% receives dose that exceeds | |
|---|---|---|---|---|---|
| Bladder constraint | 79 Gy | 74 Gy | 69 Gy | 64 Gy | |
| Rectum constraint | 74 Gy | 69 Gy | 64 Gy | 59 Gy | |
| Penile bulb | Mean dose less than or equal to 51 Gy (72.8% of PD) | ||||