TABLE 3.

Comparison of dosimetric indices for normalized Ethos and Eclipse plans. PTV coverage in the Ethos plans match their Eclipse counterpart. p‐Value is calculated using Eclipse plan as a reference

	Ethos												Eclipse
	9‐fld IMRT	σ	p‐Value	12‐fld IMRT	σ	p‐Value	2‐fld VMAT	σ	p‐Value	Ecl. reopt. 2‐fld VMAT	σ	p‐Value	2‐fld VMAT	σ
D max%	108.1	1.2	0.01	108.4	1.6	0.29	109.6	2.0	0.03	110.1	1.7	≤ 0.001	108.8	1.4
CTV V 100% (%)	99.9	0.3	0.01	99.9	0.3	0.01	99.8	0.4	0.03	99.8	0.3	0.05	99.5	0.8
Bladder V 79Gy (%)	0.0	0.0	N/A	0.0	0.0	N/A	0.0	0.0	N/A	0.0	0.0	N/A	0.0	0.0
Bladder V 74Gy (%)	0.2	0.4	0.47	0.3	0.5	0.60	0.3	0.7	0.89	0.6	1.1	0.36	0.4	1.1
Bladder V 69Gy (%)	4.6	2.9	0.88	4.5	2.9	0.65	4.6	3.3	0.73	4.6	3.3	0.80	4.6	3.8
Bladder V 64Gy (%)	6.9	3.9	0.59	6.8	3.9	0.98	6.5	4.4	0.34	6.5	4.2	0.33	6.8	5.0
Rectum V 74Gy (%)	0.0	0.2	0.67	0.0	0.1	0.71	0.0	0.1	0.64	0.1	0.2	0.24	0.0	0.1
Rectum V 69Gy (%)	1.7	1.6	0.04	1.7	1.6	0.05	1.8	1.7	0.15	1.7	1.6	0.04	2.0	1.8
Rectum V 64Gy (%)	3.3	2.6	0.37	3.2	2.6	0.12	3.3	2.6	0.24	3.2	2.6	0.11	3.5	2.9
Rectum V 59Gy (%)	5.0	3.5	0.92	4.7	3.5	0.38	4.9	3.5	0.67	4.8	3.5	0.47	5.0	3.9
Penile bulb mean dose (%)	30.8	13.7	≤ 0.001	30.6	14.0	≤ 0.001	27.4	13.3	≤ 0.001	26.2	13.6	≤ 0.001	19.4	12.1
Bladder max dose (%)	106.7	1.2	0.07	106.9	1.1	0.39	108.0	1.5	0.01	108.4	1.5	≤ 0.001	107.2	1.6
Rectum max dose (%)	100.9	8.7	0.04	101.1	8.3	0.09	101.7	9.1	0.47	101.9	9.4	0.72	102.2	8.5