TABLE 1.
Baseline characteristics of the study patients according to apo B/apo A1 ratio quartiles.
| Variables | Total (n = 1,616) |
Apo B/apo A1 ratio quartiles |
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| Q1 (<0.52) (n = 402) |
Q2 (0.52–0.66) (n = 403) |
Q3 (0.66–0.84) (n = 403) |
Q4 (>0.84) (n = 408) |
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| Age (y) | 47.5 ± 15.2 | 44.8 ± 15.0 | 46.6 ± 15.2 | 47.8 ± 14.5 | 50.7 ± 15.6 |
| Male n (%) | 966 (59.8) | 220 (54.7) | 259 (64.3) | 244 (60.5) | 243 (59.6) |
| Diabetes n (%) | 415 (25.7) | 77 (19.2) | 98 (24.3) | 106 (26.3) | 134 (32.8) |
| History of CV events n (%) | 596 (36.9) | 143 (35.6) | 135 (33.5) | 154 (38.2) | 164 (40.2) |
| Hypertension n (%) | 1,439 (89.0) | 362 (90.0) | 358 (88.8) | 365 (90.6) | 354 (86.8) |
| BMI (kg/m2) | 21.6 ± 3.1 | 20.5 ± 2.6 | 21.4 ± 3.1 | 22.1 ± 3.1 | 22.4 ± 3.3 |
| SBP (mmHg) | 136.5 ± 19.8 | 136.3 ± 20.1 | 136.7 ± 19.8 | 135.7 ± 18.5 | 137.3 ± 20.6 |
| DBP (mmHg) | 84.7 ± 14.4 | 86.1 ± 15.6 | 84.4 ± 14.1 | 84.8 ± 13.3 | 83.5 ± 14.5 |
| Hemoglobin (g/L) | 105.0 ± 21.2 | 103.5 ± 22.0 | 105.3 ± 20.9 | 107.3 ± 21.0 | 103.8 ± 20.8 |
| Serum albumin (g/L) | 37.3 ± 5.2 | 37.3 ± 5.0 | 37.2 ± 5.0 | 37.9 ± 5.0 | 36.8 ± 5.6 |
| Hs-CRP (mg/L) | 1.75 [0.64–5.74] |
1.02 [0.40–3.01] |
1.59 [0.59–4.26] |
1.87 [0.69–7.03] |
3.58 [1.11–10.04] |
| eGFR (mL/min/1.73 m2) | 6.8 ± 3.1 | 6.8 ± 2.9 | 7.1 ± 3.5 | 6.7 ± 3.2 | 6.8 ± 2.9 |
| Total Kt/V | 2.5 ± 0.7 | 2.4 ± 0.6 | 2.5 ± 0.8 | 2.5 ± 0.7 | 2.5 ± 0.7 |
| TC (mg/dL) | 196.4 ± 51.2 | 180.8 ± 41.7 | 188.2 ± 43.1 | 197.3 ± 47.5 | 218.9 ± 61.6 |
| TG (mg/dL) | 124.8 [89.4–177.0] |
100.0 [71.7–137.2] |
116.8 [85.8–163.7] |
128.3 [94.7–180.5] |
164.2 [116.2–229.2] |
| HDL-C (mg/dL) | 47.6 ± 14.9 | 57.5 ± 15.2 | 49.3 ± 13.0 | 44.7 ± 13.4 | 39.2 ± 11.6 |
| LDL-C (mg/dL) | 113.4 ± 38.7 | 97.8 ± 30.1 | 106.5 ± 31.4 | 116.7 ± 35.1 | 132.1 ± 47.1 |
| Apo B (mg/dL) | 85.0 [71.0–101.8] |
69.0 [58.0–81.0] |
80.0 [70.0–95.0] |
89.0 [78.0–102.0] |
106.5 [91.0–124.8] |
| Apo A1 (mg/dL) | 127.0 [105.0–156.0] |
163.0 [137.8–193.3] |
137.0 [117.0–157.0] |
119.0 [105.0–140.0] |
103.0 [87.0–118.0] |
| Apo B/apo A1 ratio | 0.66 [0.52–0.84] |
0.44 [0.39–0.48] |
0.59 [0.55–0.63] |
0.74 [0.70–0.78] |
0.99 [0.91–1.17] |
| Statin use n (%) | 236 (14.6) | 48 (11.9) | 57 (14.1) | 74 (18.4) | 57 (14.0) |
Means ± standard deviations (SDs) are expressed for normally distributed variables, medians and 25th–75th percentiles are expressed for non-parametric variables. Frequencies and percentages are expressed for categorical parameters. Kt/V is an important parameter for assessing the adequacy of dialysis, if the value is less than 1.7, the dialysis adequacy is thought to be not up to standard. Conversion factors for units: TC, HDL-C, and LDL-C in mg/dL to mmol/L, × 0.0259; TG in mg/dL to mmol/L, × 0.0113; Apo B and apo A1 in mg/dL to g/L, × 0.01.
Apo A1, apolipoprotein A1; Apo B, apolipoprotein B; BMI, body mass index; CV, cardiovascular; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; HDL-C, high-density lipoprotein cholesterol; Hs-CRP, hypersensitive C-reactive protein; LDL-C, low-density lipoprotein cholesterol; Q1–Q4, lowest to highest quartile; SBP, systolic blood pressure; TC, total cholesterol; TG, triglycerides.