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. 2022 Mar 25;13:870367. doi: 10.3389/fphar.2022.870367

FIGURE 1.

FIGURE 1

Terphenyllin binds to STAT3 to reduce the expression level of p-STAT3 and inhibit the STAT3 signaling pathway. (A) The chemical structure of terphenyllin. (B,C) The proposed binding mode of terphenyllin and STAT3. (D,E) MKN1 and BGC823 cells were treated with terphenyllin at the specified concentration for 24 h, and the levels of various proteins were detected by western blot analysis.