TABLE 1.
Treatment group | Total no. of patients | Hematocrit (%)b | WBC (no. [103]/μl)b | Creatinine concn (mg/dl)b | Total bilirubin concn (mg/dl)c | SGOT level (units/liter)c |
---|---|---|---|---|---|---|
CP | 30 | 40 (4) | 9.8 (6.3) | 1.1 (0.2) | 1.2 (0.8–2.0) | 37 (20–48) |
Chloroquine | 30 | 34 (9) | 6.3 (1.7) | 1.0 (0.2) | 1.0 (0.4–3.3) | 25 (10–197) |
Primaquine | 30 | 36 (6) | 6.4 (1.7) | 1.1 (0.2) | 1.1 (0.3–3.7) | 21 (8–70) |
Quinine | 22 | 38 (8) | 7.2 (2.2) | 1.1 (0.2) | 1.5 (0.7–7.6) | 19 (8–60) |
Mefloquine | 20 | 36 (9) | 8.6 (2.6) | 1.2 (0.3) | 1.9 (0.7–4.7) | 23 (10–173) |
Halofantrine | 23 | 36 (5) | 7.2 (3.2) | 1.0 (0.1) | 1.6 (0.4–3.9) | 20 (10–94) |
Artesunate | 20 | 35 (8) | 7.0 (2.7) | 1.0 (0.2) | 1.7 (0.4–4.3) | 18 (10–219) |
Artemether | 20 | 40 (5) | 7.1 (2.5) | 1.2 (.2) | 1.6 (0.3–4.9) | 21 (10–114) |
PS | 12 | 32 (9) | 6.8 (2.3) | 1.1 (0.3) | 1.9 (0.9–5.5) | 17 (10–198) |
Total | 207 | 37 (7) | 7.4 (3.9) | 1.1 (0.2) | 1.4 (0.3–7.6) | 20 (8–219) |
Abbreviations: WBC, white blood cell; SGOT, serum glutamic oxalacetic transaminase; CP, chloroquine-primaquine.
Data are means (standard deviations).
Data are means (ranges).