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. 2022 Mar 25;13:843358. doi: 10.3389/fphar.2022.843358

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Copyright © 2022 Fan, Liu, Gu, Zhang, Ye, Xi, Xia, Wang, Wang, Wang, Xu and Xiao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Biological function and pathway analysis of differentially methylated genes between the RA and Con groups. (A) GO enrichment exploration of hypermethylated peaks. (B) KEGG enrichment subclass analysis of hypermethylated peaks. (C) Top 20 KEGG pathways exploration of hypermethylated peaks. (D) GO enrichment exploration of hypomethylated peaks. (E) KEGG enrichment subclass analysis of hypomethylated peaks. (F) Top 20 KEGG pathways in the hypomethylated peaks. RA, rheumatoid arthritis; Con, control group; GO, Gene Ontology; and KEGG, Kyoto Encyclopedia of Genes and Genomes.