Table 2.
Demographics and characteristics of COVID-positive patients with and without chronic rhinosinusitis.
| No chronic rhinosinusitis | Chronic rhinosinusitis | P-value | |
|---|---|---|---|
| N | 942 | 52 | |
| Demographics | |||
| Age (in years) (SD) | 54.36 ± 0.62 | 58.14 ± 2.27 | 0.107 |
| Female sex (%) | 481 (51.06%) | 35 (67.31%) | 0.084 |
| BMI | 29.86 ± 0.46 | 28.74 ± 1.81 | 0.558 |
| Race (%) | |||
| White | 542 (57.54%) | 32 (61.54%) | 0.665 |
| Black | 256 (27.18%) | 16 (30.77%) | 0.631 |
| Symptoms | |||
| Cough | 673 (83.50%) | 38 (80.85%) | 0.686 |
| Fever | 499 (62.77%) | 19 (41.30%) | 0.639 |
| Fatigue | 330 (53.66%) | 20 (55.56%) | 0.865 |
| Shortness of breath | 370 (48.30%) | 20 (44.44%) | 0.647 |
| Diarrhea | 192 (28.96%) | 11 (26.19%) | 0.861 |
| Loss of appetite | 177 (31.49%) | 8 (24.24%) | 0.382 |
| Vomiting | 45 (6.97%) | 2 (5.13%) | 1 |
| Sore throat | 211 (22.40%) | 13 (25.00%) | 0.613 |
| Impaired sense of smell | 171 (18.17%) | 15 (28.85%) | 0.055 |
| Nasal congestion | 229 (24.31%) | 18 (34.62%) | 0.100 |
| Rhinorrhea | 132 (14.01%) | 13 (25.00%) | 0.041 |
| Loss of taste | 198 (21.02%) | 17 (32.69%) | 0.046 |
| Comorbidities | |||
| Smoking | 299 (40.08%) | 25 (50.00%) | 0.1822 |
| COPD (emphysema) | 49 (6.63%) | 9 (17.65%) | 0.0087 |
| Asthma | 130 (17.22%) | 17 (33.33%) | 0.00076 |
| Diabetes | 191 (25.23%) | 15 (30.00%) | 0.503 |
| Hypertension | 399 (51.68%) | 30 (58.82%) | 0.386 |
| Coronary artery disease | 100 (13.48%) | 12 (24.00%) | 0.056 |
| Heart failure | 89 (11.99%) | 7 (14.00%) | 0.654 |
| Cancer | 110 (14.21%) | 7 (14.29%) | 1 |
| Immunosuppressive treatment | 70 (9.07%) | 16 (32.65%) | <0.0001 |
| Sinus surgery | 4 (0.42%) | 14 (25.49%) | <0.0001 |
| Outcome | |||
| Hospitalized | 237 (25.82%) | 20 (38.46%) | 0.0355 |
| Mechanical ventilation | 53 (50.48%) | 4 (28.57%) | 0.1587 |
| ICU admission | 84 (35.59%) | 4 (20.00%) | 0.22 |
| Death | 24 (4.60%) | 1 (2.94%) | 1 |
Bolded text signifies P-values that are statistically significant.