Table 1.

Average housekeeping gene expression for each transcript and comparison

Transcripts (CT)
	TNF-αR	Fn14	IL-6R	TNF-α	TWEAK	IL-6	TRIM63	FBXO32
CTRL	22.46 ± (0.68)	22.40 ± (0.63)	22.42 ± (0.64)	22.45 ± (0.67)	22.19 ± (0.67)	22.43 ± (0.74)	22.03 ± (0.64)	22.11 ± (0.66)
SX	22.55 ± (0.83)	22.49 ± (0.84)	22.53 ± (0.88)	22.49 ± (0.86)	22.25 ± (0.92)	22.46 ± (0.89)	22.13 ± (0.84)	22.18 ± (0.84)

SX Transcripts (CT)	TKA vs. THA	MuIS− vs. MuIS+	Female vs. Male
TNF-αR	22.47 ± (0.59); 22.72 ± (2.21)	22.47 ± (0.91); 22.70 ± (0.64)	22.54 ± (0.57); 22.57 ± (1.17)
Fn14	22.37 ± (0.62); 22.75 ± (1.17)	22.37 ± (0.87); 22.72 ± (0.73)	22.47 ± (0.57); 22.52 ± (1.18)
IL-6R	22.41 ± (0.58); 22.78 ± (1.30)	22.32 ± (0.90); 22.91 ± (0.71)	22.52 ± (0.57); 22.53 ± (1.26)
TNF-α	22.36 ± (0.63); 22.78 ± (1.18)	22.35 ± (0.89); 22.76 ± (0.74)	22.52 ± (0.62); 22.44 ± (1.17)
TWEAK	22.05 ± (0.73); 22.69 ± (1.13)	22.00 ± (0.90); 22.72 ± (0.76)	22.26 ± (0.76); 22.24 ± (1.15)
IL-6	22.29 ± (0.64); 22.83 ± (1.21)	22.31 ± (0.89); 22.74 ± (0.84)	22.43 ± (0.65); 22.49 ± (1.21)
TRIM63	22.05 ± (0.57); 22.31 ± (1.24)	22.12 ± (0.91); 22.16 ± (0.71)	22.11 ± (0.57); 22.17 ± (1.18)
FBXO32	22.08 ± (0.57); 22.39 ± (1.23)	22.18 ± (0.90); 22.16 ± (0.71)	22.17 ± (0.56); 22.18 ± (1.18)

Values are means ± (SD). Housekeeping genes = GAPDH and C1orf43. Sample size: contralateral (CTRL)/surgical (SX) limbs = 70; total hip arthroplasty (THA) = 22; total knee arthroplasty (TKA) = 48; muscle inflammation susceptibility (MuIS)− = 46; MuIS+ = 24; female = 44; male = 26. FBXO32, muscle atrophy F-box (MAFbx); Fn14, fibroblast growth factor-inducible 14; IL-6, interleukin-6; IL-6R, interleukin-6 receptor; TNF-α, tumor necrosis factor alpha; TNF-αR, tumor necrosis factor alpha receptor; TRIM63, muscle ring finger-1 (MuRF1); TWEAK, TNF-like weak inducer of apoptosis.