Table 2.
comparison of miR-126-5p and miR-13 expression levels in patients with different characteristics.
| Clinicopathological features | n | miR-126-5p | t | P | miR-13 | t | P |
|---|---|---|---|---|---|---|---|
| Gender | |||||||
| Male | 95 | 15.51 ± 2.68 | 0.848 | 0.396 | 19.57 ± 2.30 | 1.066 | 0.288 |
| Female | 108 | 15.79 ± 2.01 | 19.90 ± 2.11 | ||||
| Age (years old) | |||||||
| <50 | 120 | 16.91 ± 1.73 | 0.279 | 0.780 | 18.91 ± 1.73 | 0.296 | 0.772 |
| ≥50 | 83 | 16.84 ± 1.79 | 18.84 ± 1.63 | ||||
| Lactate dehydrogenase | |||||||
| <320 | 92 | 15.65 ± 1.29 | 14.972 | <0.001 | 18.06 ± 1.22 | 0.584 | 0.560 |
| ≥320 | 111 | 17.76 ± 0.67 | 17.91 ± 2.20 | ||||
| WBC (×109/L) | |||||||
| <10 | 21 | 15.44 ± 1.16 | 0.109 | 0.914 | 18.39 ± 1.25 | 0.057 | 0.955 |
| ≥10 | 182 | 15.48 ± 1.64 | 18.37 ± 1.56 | ||||
| HGB (g/L) | |||||||
| <90 | 151 | 16.06 ± 2.47 | 6.282 | <0.001 | 18.92 ± 1.25 | 5.320 | <0.001 |
| ≥90 | 52 | 18.74 ± 3.13 | 20.21 ± 2.09 | ||||
| PLT (×109/L) | |||||||
| <50 | 149 | 16.81 ± 1.67 | 0.815 | 0.416 | 19.73 ± 2.54 | 1.105 | 0.271 |
| ≥50 | 54 | 17.05 ± 2.29 | 20.16 ± 2.18 | ||||
| Proportion of bone marrow primordial cells | |||||||
| <0.6 | 130 | 15.98 ± 2.01 | 0.171 | 0.864 | 17.67 ± 2.38 | 1.642 | 0.102 |
| ≥0.6 | 73 | 16.03 ± 1.98 | 18.21 ± 1.99 | ||||
| Hepatomegaly | |||||||
| Yes | 142 | 16.28 ± 2.11 | 0.254 | 0.800 | 18.32 ± 2.62 | 1.119 | 0.264 |
| No | 61 | 16.36 ± 1.92 | 17.81 ± 3.68 | ||||
| Splenomegaly | |||||||
| Yes | 155 | 17.87 ± 2.50 | 0.144 | 0.885 | 19.29 ± 2.75 | 1.621 | 0.107 |
| No | 48 | 17.93 ± 2.57 | 20.03 ± 2.81 | ||||
| Lymph node enlargement | |||||||
| Yes | 136 | 15.37 ± 2.56 | 0.635 | 0.526 | 18.91 ± 2.07 | 0.400 | 0.689 |
| No | 67 | 15.61 ± 2.48 | 19.04 ± 2.38 | ||||
| NPM1 | |||||||
| Mutant type | 127 | 17.23 ± 2.19 | 4.872 | <0.001 | 19.03 ± 2.16 | 6.081 | <0.001 |
| Wild type | 76 | 18.96 ± 2.83 | 20.82 ± 1.79 | ||||
| FLT3-ITD | |||||||
| Positive | 125 | 17.95 ± 2.14 | 0.200 | 0.842 | 18.55 ± 2.03 | 0.664 | 0.504 |
| Negative | 78 | 18.01 ± 1.99 | 18.76 ± 2.42 | ||||
| Complete remission | |||||||
| Yes | 181 | 19.38 ± 1.86 | 5.147 | <0.001 | 18.53 ± 2.29 | 4.620 | <0.001 |
| No | 22 | 17.21 ± 1.93 | 16.17 ± 2.10 |