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Experimental verification reveals FOXP3 involved in TMZ resistance (a). RT-qPCR analysis displayed the expression level of 4 genes in GBM-resistant strains and normal groups. (b) FOXP3 stable overexpression by LN229 and U87MG cells was verified by western blot. (c). The cell viability assay revealed that FOXP3-overexpressed GBM cell lines had a higher IC50 than the control group. ∗p < 0.05; ∗∗p < 0.01;∗∗∗p < 0.001; ns p > 0.05.
