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. 2022 Feb 16;36(4):e24293. doi: 10.1002/jcla.24293

TABLE 2.

Non‐susceptibility rates and MIC distribution of the Streptococcus pneumoniae and Streptococcus pseudopneumoniae isolates for 14 antimicrobials

Antibiotics S. pneumoniae (n = 81) S. pseudopneumoniae (n = 24)
Non‐susceptibility MIC (μg/ml) Non‐susceptibility MIC (μg/ml)
I% R% MIC50 MIC90 Range I% R% MIC50 MIC90 Range
Penicillin
Oral 56.8 13.6 0.25 2 ≤0.03–>4 54.2 16.6 0.5 2 ≤0.03–>4
Meningitis‐parenteral a 70.4 0.25 2 ≤0.03–>4 a 70.8 0.5 2 ≤0.03–>4
Nonmeningitis‐parenteral 3.7 3.7 0.25 2 ≤0.03–>4 4.2 4.2 0.5 2 ≤0.03–>4
Amoxicillin/clavulanic acid 3.7 4.9 ≤2 ≤2 ≤2–16 4.2 4.2 ≤2 ≤2 ≤2–8
Ceftriaxone
Meningitis 7.4 9.9 ≤0.12 1 ≤0.12–>2 8.4 8.4 0.25 1 ≤0.12–>2
Nonmeningitis 3.7 6.2 ≤0.12 1 ≤0.12–>2 0 8.4 0.25 1 ≤0.12–>2
Cefotaxime
Meningitis 4.9 6.2 ≤0.12 1 ≤0.12–>4 8.4 8.4 0.25 1 ≤0.12–>4
Nonmeningitis 2.5 3.7 ≤0.12 1 ≤0.12–>4 0 8.4 0.25 1 ≤0.12–>4
Cefuroxime (parenteral) 8.6 19.8 ≤0.5 ≥4 ≤0.5–>4 8.4 50 1 4 ≤0.5–>4
Meropenem 9.9 7.4 ≤0.25 0.5 ≤0.25–2 20.8 8.4 ≤0.25 0.5 ≤0.25–2
Erythromycin 3.7 74.1 >2 >2 ≤0.25–>2 0 95.8 >2 >2 ≤0.25–>2
Azithromycin 8.6 66.7 >2 >2 ≤0.25–>2 0 95.8 >2 >2 ≤0.25–>2
Chloramphenicol a 39.5 2 16 ≤1–16 a 4.2 2 4 ≤1–8
Trimethoprim/sulfamethoxazole 44.4 28.4 2 4 ≤0.5–>4 8.4 70.8 >4 >4 ≤0.5–>4
Tetracycline 4.9 82.8 >8 >8 ≤1–>8 0 91.6 >8 >8 ≤1–>8
Vancomycin a a ≤0.5 ≤0.5 ≤0.5 a a ≤0.5 ≤0.5 ≤0.5
Levofloxacin 0 0 ≤0.5 1 ≤0.5–1 0 0 1 1.5 ≤0.5–2
Moxifloxacin 0 0 ≤1 ≤1 ≤1 0 0 ≤1 ≤1 ≤1

Abbreviation: MIC, minimum inhibitory concentration.

a

No breakpoints listed.