TABLE 2.
Antibiotics | S. pneumoniae (n = 81) | S. pseudopneumoniae (n = 24) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Non‐susceptibility | MIC (μg/ml) | Non‐susceptibility | MIC (μg/ml) | |||||||
I% | R% | MIC50 | MIC90 | Range | I% | R% | MIC50 | MIC90 | Range | |
Penicillin | ||||||||||
Oral | 56.8 | 13.6 | 0.25 | 2 | ≤0.03–>4 | 54.2 | 16.6 | 0.5 | 2 | ≤0.03–>4 |
Meningitis‐parenteral | ‐ a | 70.4 | 0.25 | 2 | ≤0.03–>4 | ‐ a | 70.8 | 0.5 | 2 | ≤0.03–>4 |
Nonmeningitis‐parenteral | 3.7 | 3.7 | 0.25 | 2 | ≤0.03–>4 | 4.2 | 4.2 | 0.5 | 2 | ≤0.03–>4 |
Amoxicillin/clavulanic acid | 3.7 | 4.9 | ≤2 | ≤2 | ≤2–16 | 4.2 | 4.2 | ≤2 | ≤2 | ≤2–8 |
Ceftriaxone | ||||||||||
Meningitis | 7.4 | 9.9 | ≤0.12 | 1 | ≤0.12–>2 | 8.4 | 8.4 | 0.25 | 1 | ≤0.12–>2 |
Nonmeningitis | 3.7 | 6.2 | ≤0.12 | 1 | ≤0.12–>2 | 0 | 8.4 | 0.25 | 1 | ≤0.12–>2 |
Cefotaxime | ||||||||||
Meningitis | 4.9 | 6.2 | ≤0.12 | 1 | ≤0.12–>4 | 8.4 | 8.4 | 0.25 | 1 | ≤0.12–>4 |
Nonmeningitis | 2.5 | 3.7 | ≤0.12 | 1 | ≤0.12–>4 | 0 | 8.4 | 0.25 | 1 | ≤0.12–>4 |
Cefuroxime (parenteral) | 8.6 | 19.8 | ≤0.5 | ≥4 | ≤0.5–>4 | 8.4 | 50 | 1 | 4 | ≤0.5–>4 |
Meropenem | 9.9 | 7.4 | ≤0.25 | 0.5 | ≤0.25–2 | 20.8 | 8.4 | ≤0.25 | 0.5 | ≤0.25–2 |
Erythromycin | 3.7 | 74.1 | >2 | >2 | ≤0.25–>2 | 0 | 95.8 | >2 | >2 | ≤0.25–>2 |
Azithromycin | 8.6 | 66.7 | >2 | >2 | ≤0.25–>2 | 0 | 95.8 | >2 | >2 | ≤0.25–>2 |
Chloramphenicol | ‐ a | 39.5 | 2 | 16 | ≤1–16 | ‐ a | 4.2 | 2 | 4 | ≤1–8 |
Trimethoprim/sulfamethoxazole | 44.4 | 28.4 | 2 | 4 | ≤0.5–>4 | 8.4 | 70.8 | >4 | >4 | ≤0.5–>4 |
Tetracycline | 4.9 | 82.8 | >8 | >8 | ≤1–>8 | 0 | 91.6 | >8 | >8 | ≤1–>8 |
Vancomycin | ‐ a | ‐ a | ≤0.5 | ≤0.5 | ≤0.5 | ‐ a | ‐ a | ≤0.5 | ≤0.5 | ≤0.5 |
Levofloxacin | 0 | 0 | ≤0.5 | 1 | ≤0.5–1 | 0 | 0 | 1 | 1.5 | ≤0.5–2 |
Moxifloxacin | 0 | 0 | ≤1 | ≤1 | ≤1 | 0 | 0 | ≤1 | ≤1 | ≤1 |
Abbreviation: MIC, minimum inhibitory concentration.
No breakpoints listed.