TABLE 1.
Clinical characteristics
| Items | Sepsis patients (N = 78) |
|---|---|
| Demographics | |
| Age (years), mean ± SD | 56.6 ± 11.4 |
| Male, n (%) | 49 (62.8) |
| BMI (kg/m2), mean ± SD | 23.3 ± 3.7 |
| Smoke, n (%) | 28 (35.9) |
| Drink, n (%) | 30 (38.5) |
| History of disease, n (%) | |
| Hypertension | 33 (42.3) |
| Hyperlipidemia | 14 (17.9) |
| Diabetes | 12 (15.4) |
| CKD | 6 (7.7) |
| CCVD | 21 (26.9) |
| Disease characteristics | |
| Primary infection site, n (%) | |
| Abdominal infection | 28 (35.9) |
| Respiratory infection | 20 (25.6) |
| Skin and soft tissue infection | 16 (20.5) |
| Other infections | 14 (17.9) |
| Primary organism, n (%) | |
| G‐ bacteria | 47 (60.3) |
| G+ bacteria | 24 (30.8) |
| Fungus | 10 (12.8) |
| Others | 9 (11.5) |
| Culture negative | 11 (14.1) |
| APACHE II score, mean ± SD | 12.6 ± 6.1 |
| SOFA score, mean ± SD | 5.4 ± 2.5 |
| Respiratory system | 1.3 ± 0.6 |
| Nervous system | 0.6 ± 0.6 |
| Cardio vascular system | 0.7 ± 0.6 |
| Liver | 1.0 ± 0.6 |
| Coagulation | 1.1 ± 0.6 |
| Renal system | 0.7 ± 0.7 |
| Biochemical indexes | |
| CRP (mg/L), median (IQR) | 89.3 (44.8–128.4) |
| Th1 cells (%), median (IQR) | 16.8 (14.6–21.0) |
| IFN‐γ (pg/ml), median (IQR) | 94.0 (72.2–124.0) |
| Th17 cells (%), median (IQR) | 5.9 (5.0–6.3) |
| IL−17A (pg/ml), median (IQR) | 149.1 (90.9–212.7) |
Abbreviations: APACHE II, Acute Physiology and Chronic Health Evaluation II; BMI, body mass index; CCVD, cardiovascular and cerebrovascular diseases; CKD, chronic kidney disease; CRP, C‐reactive protein; G‐, Gram‐negative; G+, Gram‐positive; IFN‐γ, interferon gamma; IL‐17A, interleukin 17A; IQR, interquartile range; SD, standard deviation; SOFA, Sequential Organ Failure Assessment; Th1 cells, T helper 1 cells; Th17 cells, T helper 17 cells.