Fig. 3.

A 53-year-old female COVID-19 patient whose CT image was obtained 3 days after onset of clinical symptoms and assigned to the early treatment group in the original multicenter study. A Thin-section CT shows ground-glass opacities (GGOs) in the bilateral upper lobes. B Thin-section CT analyzed using the machine learning-based software shows GGOs as green areas and reticulation as a yellow area. % GGO in this case was assessed as 6%, and % consolidation as 0.3%. Probability within 4, 5, and 6 days from clinical onset determined with the combined method as 0.58, 0.58, and 0.64, respectively. CT disease severity score was 3. Prediction for this patient assigned to the early treatment group was based on %GGO, % consolidation, combined method, and CT disease severity score. After administration of favipiravir, periods for viral clearance, duration of fever, and time until hospital discharge were 1 day, 1 day, and 14 days, respectively