Table 3.
Differences between patients whose time until CT was 4 days or less and those whose time until CT was more than 4 days
| TV | SE (%) | SP (%) |
PPV (%) |
NPV (%) |
AC (%) |
Real early and late treatment groups (cases) | Viral clearance in the first 6 days (days) [median] | Duration of fever (≥ 37.5 °C or ≥ 37.0 °C) (days) [median] | Time duration until hospital discharge (days) [median] | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Radiological prediction | % GGO | 4 days or less | 10.0 ≤ | 69.2 (9/13) | 89.5 (17/19) | 81.8 (9/11) | 81.0 (17/21) |
81.3 (26/32) |
6 | 1 | 1 | 13 |
| More than 4 days | 26 | 5 | 3.5 | 23 | ||||||||
| p value | N/A | N/A | < 0.0001 | < 0.0001 | < 0.0001 | |||||||
| % Consolidation | 4 days or less | ≤ 2.0 | 100.0 (13/13) | 52.6 (10/19) | 59.1 (13/22) | 100.0 (10/10) | 71.9 (23/32) | 12 | 4 | 2 | 16 | |
| More than 4 days | 20 | 5 | 3.5 | 23.5 | ||||||||
| p value | N/A | N/A | 0.01 | 0.01 | 0.008 | |||||||
| Combined method | 4 days or less | 0.45 < | 92.3 (12/13) | 84.2 (16/19) | 80.0 (12/15) | 94.1 (16/17) | 87.5 (28/32) | 10 | 3.5 | 1.5 | 16 | |
| More than 4 days | 22 | 5 | 4 | 23 | ||||||||
| p value | N/A | N/A | 0.007 | < 0.0001 | 0.02 | |||||||
| CT disease severity score | 4 days or less | ≤ 4 | 61.5 (8/13) | 63.2 (12/19) | 57.1 (8/14) | 70.6 (12/17) | 62.5 (20/32) | 7 | 3 | 1.5 | 18 | |
| More than 4 days | 25 | 5 | 3.5 | 24 | ||||||||
| p value | N/A | GGO: p = 0.03, Combined method: p = 0.008 | N/A | 0.04 | 0.001 | 0.12 | ||||||
| Patients whose time until CT equal to or less than 4 days in early treatment group vs. patients assessed as time until CT more than 4 days in early treatment group and all patients in late treatment group | 4 days or less | N/A | 6 | 3.5 | 1.5 | 15 | ||||||
| More than 4 days | 26 | 5 | 3.5 | 23 | ||||||||
| p value | N/A | 0.04 | 0.0007 | 0.004 | ||||||||
TV threshold value, SE sensitivity, SP specificity, PPV positive predictive value, NPV negative predictive value, AC accuracy