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. 2022 Feb 28;193(1):139–149. doi: 10.1007/s10549-022-06544-0

Table 2.

Factors associated with sexual inactivity in breast cancer survivors (sexual activity as reference)

Variables Bivariate analysis Multivariable analysis
OR 95% CI OR 95% CI p value
Age at survey (years) 1.05 1.03, 1.06 1.05 1.02, 1.07  < 0.001
Not living with partner 5.05 3.78, 6.74 5.19 3.75, 7.19  < 0.001
Education ≤ 12 years 1.47 1.18, 1.83 1.08 0.83, 1.41 0.56
No paid work at survey 1.81 1.45, 2.27 0.93 0.68, 1.26 0.62
Mastectomy (BCT = ref) 0.95 0.76, 1.18
Chemotherapy 1.01 0.80, 1.27
Radiotherapy 0.97 0.74, 1.27
Endocrine treatment (ET)
 No ET (ref)
 Aromatase inhibitor 1.53 1.17, 2.00 1.73 1.23, 2.43 0.002
 Tamoxifen 0.76 0.58, 1.00 1.03 0.71, 1.51 0.87
 Unknown type 1.54 0.92, 2.59 1.24 0.66, 2.33 0.50
 ET at present 0.76 0.59, 0.99 1.09 0.76, 1.56 0.64
Somatic comorbidity
 No disease (ref)
 1–2 comorbid disease(s) 1.52 1.15, 2.01 1.22 0.88, 1.71 0.24
 ≥ 3 comorbid diseases 2.52 1.81, 3.51 1.29 0.83, 2.00 0.26
 Sleep problems 1.49 1.20, 1.86 1.15 0.87, 1.52 0.32
 Paina 1.01 1.01, 1.01 1.00 1.00, 1.01 0.74
 Breast symptomsa 1.01 1.00, 1.02 1.00 1.00, 1.01 0.46
 Body imagea 0.99 0.99, 0.995 0.99 0.99, 0.995 0.003
 Chronic fatigue 1.44 1.14, 1.82 1.30 0.95, 1.79 0.10
 Obesity 1.60 1.20, 2.13 1.30 0.91, 1.85 0.15
 Physically inactive 1.58 1.26, 1.98 1.21 0.93, 1.58 0.16
 Anxiety disorder 1.62 1.05, 2.50 1.13 0.65, 1.99 0.66
 Major depression 1.82 1.36, 2.43 1.20 0.79, 1.83 0.39

Bold statistically significant (p < 0.05)

OR odds ratio, CI confidence interval, BCT breast-conserving therapy

aScale 0–100 (a higher score corresponds to more pain and breast symptoms and a better body image).