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. 2000 Jun;44(6):1705–1707. doi: 10.1128/aac.44.6.1705-1707.2000

TABLE 1.

Antimicrobial susceptibilities of serogroup C and meningococci of other serogroups or nongroupable meningococci from patients and carriers

Isolate group and antibiotic MIC (μg/ml)
% Strainsa
Range 50% 90% S I R
Clinical isolates (n = 112)
 Serogroup C (n = 72)
  Penicillin 0.015–0.5 0.12 0.25 33.3 66.7 0.0
  Ampicillin 0.03–0.5 0.25 0.5 5.6 94.4 0.0
  Cefotaxime ≤0.0003–0.015 0.003 0.007 100.0  —b
  Ceftriaxone 0.0003–0.0015 0.0007 0.0015 100.0
  Rifampin ≤0.007–0.12 0.03 0.12 100.0 0.0
  Ciprofloxacin 0.003–0.006 0.006 0.006 100.0 0.0 0.0
  Sulfadiazine 25–>100 100 >100 0.0 100.0
 Non-serogroup C (n = 40)
  Penicillin ≤0.007–0.12 0.06 0.12 65.0 35.0 0.0
  Ampicillin 0.015–0.5 0.12 0.25 40.0 60.0 0.0
  Cefotaxime ≤0.0003–0.015 0.003 0.007 100.0
  Ceftriaxone 0.0003–0.0015 0.0007 0.0015 100.0
  Rifampin ≤0.007–0.12 0.03 0.12 100.0 0.0
  Ciprofloxacin 0.003–0.006 0.006 0.006 100.0 0.0 0.0
  Sulfadiazine ≤1–>100 25 100 15.0 85.0
Carrier isolates (n = 789)
 Serogroup C (n = 89)
  Penicillin ≤0.007–0.5 0.12 0.25 36.0 64.0 0.0
  Ampicillin 0.03–1 0.25 0.5 13.5 86.5 0.0
  Cefotaxime 0.0007–0.015 0.003 0.007 100.0
  Ceftriaxone 0.00015–0.007 0.0015 0.0015 100.0
  Rifampin ≤0.007–0.25 0.03 0.12 100.0 0.0
  Ciprofloxacin 0.0015–0.006 0.006 0.006 100.0 0.0 0.0
  Sulfadiazine 5–>100 >100 >100 4.5 95.5
 Non-serogroup C (n = 700)
  Penicillin ≤0.007–0.5 0.06 0.25 64.1 35.9 0.0
  Ampicillin ≤0.007–1 0.12 0.5 37.1 62.9 0.0
  Cefotaxime ≤0.0003–0.03 0.003 0.007 100.0
  Ceftriaxone ≤0.00007–0.015 0.0007 0.0015 100.0
  Rifampin ≤0.007–2 0.03 0.12 100.0 0.0
  Ciprofloxacin ≤0.0003–0.012 0.006 0.006 100.0 0.0 0.0
  Sulfadiazine ≤1–>100 100 >100 7.7 92.3
a

S, I, and R, susceptible, intermediate, and resistant, respectively. 

b

—, category not determined.