TABLE 1.
Isolate group and antibiotic | MIC (μg/ml)
|
% Strainsa
|
||||
---|---|---|---|---|---|---|
Range | 50% | 90% | S | I | R | |
Clinical isolates (n = 112) | ||||||
Serogroup C (n = 72) | ||||||
Penicillin | 0.015–0.5 | 0.12 | 0.25 | 33.3 | 66.7 | 0.0 |
Ampicillin | 0.03–0.5 | 0.25 | 0.5 | 5.6 | 94.4 | 0.0 |
Cefotaxime | ≤0.0003–0.015 | 0.003 | 0.007 | 100.0 | —b | — |
Ceftriaxone | 0.0003–0.0015 | 0.0007 | 0.0015 | 100.0 | — | — |
Rifampin | ≤0.007–0.12 | 0.03 | 0.12 | 100.0 | — | 0.0 |
Ciprofloxacin | 0.003–0.006 | 0.006 | 0.006 | 100.0 | 0.0 | 0.0 |
Sulfadiazine | 25–>100 | 100 | >100 | 0.0 | — | 100.0 |
Non-serogroup C (n = 40) | ||||||
Penicillin | ≤0.007–0.12 | 0.06 | 0.12 | 65.0 | 35.0 | 0.0 |
Ampicillin | 0.015–0.5 | 0.12 | 0.25 | 40.0 | 60.0 | 0.0 |
Cefotaxime | ≤0.0003–0.015 | 0.003 | 0.007 | 100.0 | — | — |
Ceftriaxone | 0.0003–0.0015 | 0.0007 | 0.0015 | 100.0 | — | — |
Rifampin | ≤0.007–0.12 | 0.03 | 0.12 | 100.0 | — | 0.0 |
Ciprofloxacin | 0.003–0.006 | 0.006 | 0.006 | 100.0 | 0.0 | 0.0 |
Sulfadiazine | ≤1–>100 | 25 | 100 | 15.0 | — | 85.0 |
Carrier isolates (n = 789) | ||||||
Serogroup C (n = 89) | ||||||
Penicillin | ≤0.007–0.5 | 0.12 | 0.25 | 36.0 | 64.0 | 0.0 |
Ampicillin | 0.03–1 | 0.25 | 0.5 | 13.5 | 86.5 | 0.0 |
Cefotaxime | 0.0007–0.015 | 0.003 | 0.007 | 100.0 | — | — |
Ceftriaxone | 0.00015–0.007 | 0.0015 | 0.0015 | 100.0 | — | — |
Rifampin | ≤0.007–0.25 | 0.03 | 0.12 | 100.0 | — | 0.0 |
Ciprofloxacin | 0.0015–0.006 | 0.006 | 0.006 | 100.0 | 0.0 | 0.0 |
Sulfadiazine | 5–>100 | >100 | >100 | 4.5 | — | 95.5 |
Non-serogroup C (n = 700) | ||||||
Penicillin | ≤0.007–0.5 | 0.06 | 0.25 | 64.1 | 35.9 | 0.0 |
Ampicillin | ≤0.007–1 | 0.12 | 0.5 | 37.1 | 62.9 | 0.0 |
Cefotaxime | ≤0.0003–0.03 | 0.003 | 0.007 | 100.0 | — | — |
Ceftriaxone | ≤0.00007–0.015 | 0.0007 | 0.0015 | 100.0 | — | — |
Rifampin | ≤0.007–2 | 0.03 | 0.12 | 100.0 | — | 0.0 |
Ciprofloxacin | ≤0.0003–0.012 | 0.006 | 0.006 | 100.0 | 0.0 | 0.0 |
Sulfadiazine | ≤1–>100 | 100 | >100 | 7.7 | — | 92.3 |
S, I, and R, susceptible, intermediate, and resistant, respectively.
—, category not determined.