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. 2022 Apr 8;12:5916. doi: 10.1038/s41598-022-09908-0

Table 4.

The association between CD36 rs1761667 polymorphism and blood pressure and fasting blood glucose. All analyses were conducted using a random-effects modela.

No. of data-sets No. of subjects Meta-analysis Heterogeneity
WMD2 (95%CI) Peffect Q statistic Pwithin I2 (%)
Systolic Blood pressure (mmHg) b
Allelic model (A vs. G) 5 4224 − 2.01 (− 4.92, 0.90) 0.17 36.92  < 0.001 89.20
Dominant model (AA + GA vs. GG) 2112 − 4.17 (− 9.22, 0.88) 0.10 38.98  < 0.001 89.70
Recessive model (AA vs. GA + GG) 2112 − 4.83 (− 12.95, 3.28) 0.24 126.85  < 0.001 96.80
Homozygous model (AA vs. GG) 1050 − 8.42 (− 18.09, 1.24) 0.08 85.03  < 0.001 95.30
Heterozygous model (GA vs. GG) 1669 − 3.30 (− 7.84, 1.23) 0.15 28.79  < 0.001 86.10
Diastolic Blood pressure (mmHg) b
Allelic model (A vs. G) 6 4448 − 0.14 (− 0.75, 0.46) 0.63 4.89 0.43 0.00
Dominant model (AA + GA vs. GG) 2224 − 0.14 (− 1.20, 0.92) 0.79 0.87 0.97 0.00
Recessive model (AA vs. GA + GG) 2224 − 0.85 (− 2.56, 0.85) 0.32 9.50 0.08 47.70
Homozygous model (AA vs. GG) 1113 − 0.57 (− 2.14, 1.00) 0.47 5.87 0.31 14.80
Heterozygous model (GA vs. GG) 1759 0.001 (− 1.11, 1.11) 0.99 0.33 0.99 0.00
Fasting blood glucose (mg/dl) b
Allelic model (A vs. G) 7 4610 2.07 (− 0.11, 4.25) 0.06 23.76 0.001 74.70
Dominant model (AA + GA vs. GG) 2305 3.64 (− 0.89, 8.17) 0.11 49.96  < 0.001 0.88
Recessive model (AA vs. GA + GG) 2305 2.33 (0.92, 3.74) 0.001 6.03 0.42 0.40
Homozygous model (AA vs. GG) 1173 4.28 (− 1.02, 9.60) 0.11 30.42  < 0.001 80.30
Heterozygous model (GA vs. GG) 1813 3.07 (− 1.17, 7.33) 0.15 39.95  < 0.001 85.00

Significant values are in bold.

aAll analyses were done using the random-effects model.

bThere was no evidence of publication bias by observing the funnel plots.

WMD, weighted mean difference; 95% CI, 95% confidence interval.