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. 2022 Apr 8;5:47. doi: 10.1038/s41746-022-00590-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Depicted are time-dependent receiver operating characteristic curves for the Pooled Cohort Equations (PCE, left panels) and the CHARGE-AF score (right panels) in C3PO (top panels) versus the respective Convenience Samples (bottom panels). Each plot shows the discrimination performance of each risk score for its respective prediction target (i.e., 10-year MI/stroke for the PCE, 5-year incident AF for CHARGE-AF). Since the PCE score comprises four models stratified on the basis of sex and race, the curves for each score are represented separately (see legend). The c-index calculated using the inverse probability of censoring weighting method²⁸ is depicted for each model.