Table 2.

Age wise distribution of gene mutations frequency in 111 MDS patients.

Genes	Frequency (N = 111)	Younger (N = 55) (≤ 59 years)	Older (N = 56) (> 59 years)	p value
SF3B1	28 (25.2%)	12 (21.8%)	16 (28.6%)	0.050
SRSF2	22 (19.8%)	14 (25.5%)	8 (14.3%)	0.176
U2AF1	16 (14.4%)	5 (9.1%)	11 (19.6%)	0.569
ASXL1	11 (9.9%)	4 (7.3%)	7 (12.5%)	0.357
RUNX1	11 (9.9%)	5 (9.1%)	6 (10.7%)	0.569
TET2	10 (9%)	2 (3.6%)	8 (14.3%)	0.311
TP53	10 (9%)	7 (12.7%)	3 (5.4%)	0.662
ATM	7 (6.3%)	5 (9.1%)	2 (3.6%)	0.990
NRAS	6 (5.4%)	3 (5.5%)	3 (5.5%)	0.150
JAK2/3	6 (5.4%)	5 (9.1%)	1 (1.8%)	0.990
DNMT3A	5 (4.5%)	1 (1.8%)	4 (7.1%)	0.311
KMT2D	5 (4.5%)	2 (3.6%)	3 (5.4%)	0.319
NOTCH1	5 (4.5%)	3 (5.5%)	2 (3.6%)	0.319
ZRSR2	5 (4.5%)	2 (3.6%)	3 (5.4%)	0.175
SETBP1	5 (4.5%)	2 (3.6)	3 (5.4%)	0.775
KRAS	4 (3.6%)	3 (5.5%)	1 (1.8%)	0.982
NPM1	4 (3.6%)	2 (3.6%)	2 (3.6%)	0.3
IDH1/2	3 (2.7%)	1 (1.8%)	2 (93.6%)	0.632
BCOR	3 (2.7%)	1 (1.8%)	2 (3.6%)	0.14
Other genes	2–1 (1.8–0.9%)	–	–	–