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. 2022 Apr 8;12:5925. doi: 10.1038/s41598-022-09864-9

Table 4.

Kaplan–Meier Survival analysis of patients with mutations in MDS.

Mutation variable Mutational status N Median OS (Months) p value
TET2 MT 10 31.5 0.136
WT 142 60
DNMT3A MT 5 NR 0.79
WT 147 60
ASXL1 MT 11 14 0.0261
WT 141 60
RUNX1 MT 11 24 0.075
WT 141 72
TP53 MT 9 5 < 0.0001
WT 143 60
SF3B1 MT 28 48 0.79
WT 124 72
SRSF2 MT 22 52 0.121
WT 130 48
U2AF1 MT 16 NR 0.402
WT 136 52
JAK2/3 MT 6 10 0.039
WT 146 60
KRAS MT 4 12 0.019
WT 148 60
NRAS MT 6 13 0.012
WT 146 60
NOTCH1 MT 5 13 0.11
WT 147 60
NPM1 MT 4 21 0.41
WT 148 60