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. 2022 Apr 8;5:335. doi: 10.1038/s42003-022-03238-7

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Oncoplot showing recurrence of known OAC driver gene mutations (taken from Frankell et al., 2019 and Campbell et al., 2020) with and without SV. Estimates of recurrence without SVs includes copy number gains and losses, INDELs and SNVs. Recurrence with SVs are counted when the interval between two breakpoints overlaps with exon or exons of the gene. Two-proportions z-test with multiple hypothesis testing (FDR) used to test if recurrence is significantly higher with SVs included.