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. 2022 Apr 9;28:40. doi: 10.1186/s10020-022-00465-w

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Proteomic changes in CACs in response to the serum of COVID-19 asymptomatic patients. Volcano plots representing proteins up- (red) or down- (green) regulated between CACs treated with A the serum of COVID-19 PCR + vs Negative donors (CACs + PCR), or B the serum of IgG + (CACs + IgG) vs COVID-19 negative donors (CACs + Neg). C Schematic representation of the number of proteins up- (red) or down- regulated (green) in CACs + PCR or CACs + IgG compared to CACs + Neg controls. D Venn’s diagram including the number of proteins up- or down-regulated, common or exclusive in CACs + PCR vs CACs + Neg, or in CACs + IgG vs CAC + Neg. E Hierarchical cluster representing the differential protein profiles for CACs + PCR, CACs + IgG or CACs + Neg