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. 2022 Apr 9;28:40. doi: 10.1186/s10020-022-00465-w

Fig. 6.

Fig. 6

Interactions between proteins altered in serum and CACs samples. A Venn’s diagram including the number of proteins up- or down-regulated, common or exclusive in serum samples and CACs + PCR vs CACs + Neg and CACs + IgG vs CACs + Neg comparisons. B An in-silico analysis evaluating the potential interactions between altered proteins in the serum of COVID-19 asymptomatic donors (PCR + and IgG +) and the proteins altered in healthy CACs in response to those serums was performed with PINA v3 on-line platform. C One of the most representative functions found between the interactions found between both sets (serum and CACs) of altered proteins was platelet activation, including platelet aggregation and degranulation. Figure obtained with Reactome