TABLE 1.
Characteristic | Nonventilated HABP | Ventilated HABP | Ventilator-Associated Bacterial Pneumonia | ||||
---|---|---|---|---|---|---|---|
n = 4,728 | % | n = 4,561 | % | n = 8,530 | % | p | |
Mean age, yr (sd) | 66.7 (15.1) | 65.7 (14.0) | 59.7 (16.6) | < 0.001 | |||
Gender: male | 2,845 | 60.17 | 2,921 | 64.04 | 5,557 | 65.15 | < 0.001 |
Charlson Comorbidity Score | |||||||
Mean (sd) | 3.9 (2.8) | 4.1 (2.8) | 3.2 (2.5) | < 0.001 | |||
Median (interquartile range) | 3 (2–5) | 4 (2–6) | 3 (1–5) | < 0.001 | |||
Illness severity measures by day 2 from infection onset | |||||||
ICU admission | 2,742 | 57.99 | 4,287 | 93.99 | 8,162 | 95.69 | < 0.001 |
Vasopressors | 365 | 7.72 | 1,770 | 38.81 | 2,103 | 24.65 | |
Severe sepsis | 627 | 13.26 | 1,166 | 25.56 | 1,393 | 16.33 | < 0.001 |
Septic shock | 557 | 11.78 | 1,472 | 32.27 | 1,603 | 18.79 | < 0.001 |
Empiric treatment appropriateness | |||||||
Non-IET | 3,856 | 81.56 | 3,929 | 86.14 | 7,178 | 84.15 | < 0.001 |
IET | 403 | 8.52 | 254 | 5.57 | 615 | 7.21 | |
Indeterminate | 469 | 9.92 | 378 | 8.29 | 737 | 8.64 |