Table 5.

Phenotype Comparison Between Different FZD4 Domains

Domains	Others, n	CRD, n	7 Transmembrane Domains, n	Amino Acids 495–537, n	P Value
Stages					0.725
1	5	8	9	2
2	2	5	5	4
3	0	8	7	2
4	8	18	13	4
5	1	6	3	1
Folds					0.657
Yes	8	30	29	10
No	8	16	14	5
Retinal detachment					0.574
Yes	13	47	37	13
No	1	7	6	3
TEMPVIA					0.740
Yes	3	5	7	0
No	3	4	7	2
Foveal hypoplasia					1.000
Yes	2	5	4	0
No	4	11	8	2

TEMPVIA, temporal mid-peripheral vitreoretinal interface abnormality.

CRD, cysteine-rich domain.