Skip to main content
. 2022 Apr 9;22:376. doi: 10.1186/s12885-022-09374-x

Table 5.

Uni- and multivariate Hazard Cox regression analysis of RFS in recurrent cancer biopsiesa

Univariate Multivariate
HR 95% CI p-values HR 95% CI p-values
Age 1.00 .97 1.03 0.888 1.00 .97 1.03 0.987
CXCR4high vs CXCR4low 0.49 .25 .93 0.031 0.57 .24 1.33 0.193
Residual disease <2cm 1.13 .56 2.28 0.724 0.81 .36 1.84 0.619
Residual disease >2cm 3.67 1.62 8.31 0.002 2.48 .88 6.95 0.085
N of chemotherapy cycles 1.28 1.05 1.55 0.013 1.16 .36 3.73 0.800
FIGO IIIA 0.34 .02 5.72 0.455 0.30 .01 6.91 0.449
FIGO IIIB 0.93 .11 8.04 0.944 0.64 .07 6.27 0.705
FIGO IIIC 1.21 .16 9.03 0.851 0.85 .10 7.08 0.884
FIGO IV 1.48 .18 11.94 0.712 0.92 .10 8.22 0.939

a Cut-off = 84 cells/punch, n = 43. Multivariate analyses showing Hazard Ratios and p-value for all recurrent cancer biopsies (n = 42 less than 44 due to missing value) conferred by categorized CXCR4 expression by tumor cells, age, residual disease after cytoreductive surgery, number of chemotherapy cycles and FIGO classification.