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. 2022 Apr 9;20:2091–2111. doi: 10.1016/j.csbj.2022.04.010

Fig. 15.

Fig. 15

COVID-19 assay comparing NTV (PF07321332), 2-BDN (BisD nitrile), 2-BV6 (BisD tetrazole). Vero cells infected with SARS-Cov-2 were treated with the different compounds. The cytopathic effect (CPE) was measured under an inverted microscope and expressed as a percentage to the CPE observed in untreated cells. The 2-BDN and 2-BV6 bisartans bear the butyl group at position 2 of the imidazole ring as in losartan. Details of the study are seen in the supplementary material.