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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Nature. 2021 Dec 15;601(7893):397–403. doi: 10.1038/s41586-021-04230-7

Figure 1. STICR-labeled progenitors generate all three principal cortical cell types.

Figure 1.

a) Lentiviral vector design of STICR b) Schematic of experimental design used to label and capture samples. c) UMAP embedding and Louvain clustering of STICR-labeled cells following scRNA-seq. d) Feature plot of principal cell trajectory marker genes DLX2 (GABAergic inhibitory neurons and DLX2+ IPCs), NEUROD2 (excitatory neurons), GFAP (glia), and EOMES (EOMES+ IPCs). e) Histogram of clone sizes within each sample. Left, clone sizes from 1–75 cells. Right, clone sizes of >75 cells in 25 cell bins.