Table 4.
Comparison between patients with normal/abnormal CT at 12 months (n = 47)
| Variable | Normal CT (n = 31) | Abnormal CT (n = 28) | p | |
|---|---|---|---|---|
| Age, median (1st–3rd quartiles) | 60 (56–72) | 71.5 (66–78) | 0.06 | |
| Male, n (%) | 13 (76.4) | 18 (60) | 0.25 | |
| BMI (kg/m2), median (1st–3rd quartiles) | 25.8 (24.3–28.6) | 25.6 (23.5–27) | 0.44 | |
| Smoking habit, n (%) | 10 (58.7) | 10 (33.3) | 0.23 | |
| Symptoms, n (%) | ||||
| Dyspnea | 3 (17.6) | 7 (23.3) | 0.64 | |
| Cough | 0 (0) | 3 (10) | 0.17 | |
| Fatigue | 1 (5.8) | 6 (20) | 0.19 | |
| Anxiety | 11 (64.7) | 14 (46.6) | 0.23 | |
| Depression | 13 (76.4) | 18 (60) | 0.39 | |
| 6MWT, median (1st–3rd quartiles) | 377 (368–395) | 353.5 (339–387.5) | 0.52 | |
| Desaturation at 6MWT, n (%) | 2 (14.3) | 5 (18.5) | 0.73 | |
| PFTs, median (1st–3rd quartiles) | ||||
| FVC | 94 (86.5–113) | 99 (88–108) | 0.97 | |
| FEV1 | 99 (91.5–117.5) | 97.5 (86–110) | 0.51 | |
| FEF25-75 | 103.5 (73–114.5) | 75 (51.5–110) | 0.11 | |
| TLC | 101 (92–108) | 93.5 (82.5–108) | 0.22 | |
| DLCO | 79 (70–93) | 70 (62–78) | 0.01 | |
| Reduced DLCO, n (%) | 4 (26.6) | 17 (63) | 0.02 | |