Table 2.
Summary of the findings in relation to breathing exercises via telerehabilitation.
Breathing exercises compared with no intervention for COVID-19 | ||||||
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Patient or population: COVID-19 | Setting: home-based | Intervention: breathing exercises | Comparison: no intervention | ||||||
Outcomes | Anticipated absolute effectsa (95% CI) |
Relative effect (95% CI) | Number of participants (studies) | Certainty of the evidence (GRADE) | Comments | |
Risk with no intervention | Risk with breathing exercises | |||||
Functional capacity at 2 wks: 6-minute walk test | The mean change in functional capacity at 2 wks ranged from –3.23 to 6 m | MD 101 m higher (61 higher to 141 higher) | – | 89 (2) | ⊕⊕○○ Lowb,c |
Breathing exercises may slightly increase functional capacity at 2 wks. |
Performance at 2 wks: 30-second sit-to-stand | The mean change in performance at 2 wks ranged from –0.59 to –0.31 repetitions | MD 2.2 repetitions higher (1.5 higher to 2.8 higher) | – | 89 (2) | ⊕⊕○○ Lowb,c |
Breathing exercises may slightly increase performance at 2 wks. |
Dyspnoea at 2 wks: Multidimensional Dyspnoea-12 | The mean change in dyspnoea at 2 wks ranged from 0.05 to 0.32 | MD 6 lower (7 lower to 5 lower) | – | 89 (2) | ⊕⊕○○ Lowb,c |
Breathing exercises may slightly reduce dyspnoea at 2 wks. |
Perceived effort at 2 wks: Borg scale | The mean change in perceived effort at 2 wks ranged from –0.32 to 0.14 | MD 2.8 lower (3.3 lower to 2.3 lower) | – | 89 (2) | ⊕⊕○○ Lowb,c |
Breathing exercises may result in a slight reduction in perceived effort at 2 wks. |
GRADE Working Group grades of evidence: High certainty: we are very confident that the true effect lies close to that of the estimate of the effect; Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different; Low certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect; Very low certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect. | ||||||
The risk in the intervention group (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
Downgraded one level due to serious risk of bias (some concerns due to deviations from intended interventions and selection of the reported result).
Downgraded one level due to serious imprecision (few participants and studies).