Table 1.
Multivariate Adjusted Odds Ratios for the Association Between ACTH Levels and PSD at 3 months
| ACTH (pg/mL) | Unadjusted Model | Model 1 | Model 2 | Model 3 | ||||
|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
| 0.004 | 0.005 | 0.005 | 0.017 | |||||
| T1, n=255 | 1 (Reference) | … | 1 (Reference) | … | 1 (Reference) | … | 1 (Reference) | |
| T2, n=257 | 1.717 (1.196–2.464) | 0.003 | 1.660 (1.147–2.401) | 0.007 | 1.660 (1.147–2.401) | 0.007 | 1.496 (1.019–2.194) | 0.040 |
| T3, n=256 | 1.701 (1.185–2.443) | 0.004 | 1.790 (1.230–2.605) | 0.002 | 1.790 (1.230–2.605) | 0.002 | 1.735 (1.176–2.560) | 0.005 |
Notes: Reference OR (1.000) is the lowest level of ACTH for PSD. Model 1: adjusted for age, sex, BMI, sleep time, education levels, smoking, drinking and physical activity. Model 2: adjusted for covariates from model 1 and further adjusted for hypertension, diabetes mellitus, hyperlipidemia and coronary artery disease. Model 3: adjusted for covariates from model 2 and further adjusted for baseline NIHSS, BI and mRS.
Abbreviations: OR, odds ratio; CI, confidence level; PSD, post-stroke depression.