Table 1.
Downregulated genes after exposure to Gulf War insult. Green, negative fold changes indicate downregulation.
| Symbol | Entrez Gene Name | RPKM | FC | P-value |
|---|---|---|---|---|
| Arc | Activity regulated cytoskeleton associated protein | 33.6 | −1.553 | 8.72E-05 |
| Egr1 | Early growth response 1 | 23.3 | −1.497 | 9.77E-05 |
| Nr4a1 | Nuclear receptor subfamily 4 group A member 1 | 16.5 | −1.449 | 0.000608 |
| Apod | Apolipoprotein D | 32.5 | −1.353 | 0.000973 |
| Hba-a2 | Hemoglobin alpha, adult chain 2 | 60.7 | −1.350 | 0.00485 |
| Tmem88b | Transmembrane protein 88B | 16.5 | −1.350 | 0.00107 |
| Wfs1 | Wolframin ER transmembrane glycoprotein | 33.2 | −1.321 | 0.00357 |
| Junb | JunB proto-oncogene, AP-1 transcription factor subunit | 36.6 | −1.308 | 0.00847 |
| Fam163b | Family with sequence similarity 163 member B | 52.3 | −1.306 | 0.00959 |
| Mog | Myelin oligodendrocyte glycoprotein | 22.7 | −1.288 | 0.00659 |
| Mbp | Myelin basic protein | 281.4 | −1.284 | 0.0115 |
| Bcas1 | Breast carcinoma amplified sequence 1 | 41.5 | −1.277 | 0.00483 |
| Cd9 | CD9 molecule | 29.2 | −1.268 | 0.0134 |
| Gsn | Gelsolin | 15.9 | −1.267 | 0.0138 |
| Pllp | Plasmolipin | 21.3 | −1.267 | 0.018 |
| Mag | Myelin associated glycoprotein | 50.6 | −1.263 | 0.00963 |
| Nutf2-ps1 | Nuclear transport factor 2, pseudogene 1 | 19.1 | −1.263 | 0.0167 |
| Pcp4l1 | Purkinje cell protein 4-like 1 | 26.7 | −1.263 | 0.0239 |
| H2-D1 | Histocompatibility 2, D region locus 1 | 11.8 | −1.259 | 0.0115 |
| Trf | Transferrin | 62.8 | −1.257 | 0.0107 |
| Rpl10-ps3 | Ribosomal protein L10, pseudogene 3 | 75.6 | −1.255 | 0.0296 |
| Plekhb1 | Pleckstrin homology domain containing B1 | 65.3 | −1.254 | 0.00647 |
| Srebf1 | Sterol regulatory element binding transcription factor 1 | 11.2 | −1.247 | 0.017 |
| Cnp | 2’,3’-cyclic nucleotide 3’ phosphodiesterase | 105.7 | −1.246 | 0.0137 |
| Septin4 | Septin 4 | 27.6 | −1.244 | 0.0125 |
| Slco1c1 | Solute carrier organic anion transporter family member 1C1 | 11.2 | −1.243 | 0.0349 |
| Pltp | Phospholipid transfer protein | 21.6 | −1.242 | 0.0352 |
| Cldn11 | Claudin 11 | 73.5 | −1.240 | 0.0169 |
| Fa2h | Fatty acid 2-hydroxylase | 11.0 | −1.239 | 0.0267 |
| Rhog | Ras homolog family member G | 12.3 | −1.238 | 0.0359 |
| Prr18 | Proline rich 18 | 17.0 | −1.229 | 0.0231 |
| Egr4 | Early growth response 4 | 16.8 | −1.228 | 0.0849 |
| mt-Atp8 | ATP synthase F0 subunit 8 | 7509.7 | −1.225 | 0.0323 |
| C1ql2 | Complement C1q like 2 | 40.4 | −1.222 | 0.0578 |
| Nfkbia | NFKB inhibitor alpha | 12.4 | −1.221 | 0.0608 |
| Igfbp5 | Insulin like growth factor binding protein 5 | 23.2 | −1.219 | 0.0112 |
| B2m | Beta-2-microglobulin | 57.4 | −1.217 | 0.0348 |
| Hbb-bs | Hemoglobin subunit beta | 45.2 | −1.215 | 0.0521 |
| S100a16 | S100 calcium binding protein A16 | 20.3 | −1.211 | 0.0518 |
| mt-Atp6 | ATP synthase F0 subunit 6 | 8936.0 | −1.210 | 0.0481 |
| Slc6a6 | Solute carrier family 6 member 6 | 15.6 | −1.208 | 0.0185 |
| Ddit4 | DNA damage inducible transcript 4 | 38.8 | −1.204 | 0.0563 |
| Anxa5 | Annexin A5 | 15.5 | −1.203 | 0.0383 |
| S100a1 | S100 calcium binding protein A1 | 35.3 | −1.202 | 0.0469 |
| Chrm3 | Cholinergic receptor muscarinic 3 | 10.5 | −1.200 | 0.0652 |