Table 4a.
Subset of significantly affected gene ontology categories involved in biological processes. Green, negative fold changes indicate downregulation. Red, positive fold changes indicate upregulation.
| GO term | Description | Detected Genes | DE Genes | DE Genes (Names) | P-values |
|---|---|---|---|---|---|
| 0110077 | Vesicle-mediated intercellular transport | 1 | 1 | Arc | 2.89E-4 |
| 0006429 | Leucyl-tRNA aminoacylation | 2 | 1 | Lars2 | 5.78E-4 |
| 0050767 | Regulation of neurogenesis | 934 | 3 | Arc, Gh, Opalin | 1.45E-3 |
| 0006518 | Peptide metabolic process | 262 | 2 | Hmgn5, Lars2 | 2.22E-3 |
| 0090031 | Positive regulation of steroid hormone biosynthetic process | 9 | 1 | Gh | 2.60E-3 |
| 2000969 | Positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity | 9 | 1 | Arc | 2.60E-3 |
| 0032094 | Response to food | 12 | 1 | Gh | 3.47E-3 |
| 0043603 | Cellular amide metabolic process | 392 | 2 | Hmgn5, Lars2 | 4.90E-3 |
| 1900452 | Regulation of long-term synaptic depression | 17 | 1 | Arc | 4.91E-3 |
| 0007405 | Neuroblast proliferation | 19 | 1 | Gh | 5.48E-3 |
| 0099149 | Regulation of postsynaptic neurotransmitter receptor internalization | 23 | 1 | Arc | 6.64E-3 |
| 0032543 | Mitochondrial translation | 31 | 1 | Lars2 | 8.94E-3 |
| 0007616 | Long-term memory | 39 | 1 | Arc | 0.0112 |
| 0007492 | Endoderm development | 40 | 1 | Arc | 0.0115 |
| 0040018 | Positive regulation of multicellular organism growth | 42 | 1 | Gh | 0.0121 |
| 0072089 | Stem cell proliferation | 45 | 1 | Gh | 0.0129 |
| 0048286 | Lung alveolus development | 49 | 1 | Gh | 0.0141 |
| 0048713 | Regulation of oligodendrocyte differentiation | 49 | 1 | Opalin | 0.0141 |
| 0010828 | Positive regulation of glucose transport | 50 | 1 | Gh | 0.0144 |
| 0051028 | mRNA transport | 52 | 1 | Arc | 0.0149 |
| 1900271 | Regulation of long-term synaptic potentiation | 54 | 1 | Arc | 0.0155 |
| 0006749 | Glutathione metabolic process | 55 | 1 | Hmgn5 | 0.0158 |
| 0061001 | Regulation of dendritic spine morphogenesis | 56 | 1 | Arc | 0.0161 |
| 0099601 | Regulation of neurotransmitter receptor activity | 60 | 1 | Arc | 0.0172 |
| 0061351 | Neural precursor cell proliferation | 63 | 1 | Gh | 0.0181 |
| 0048168 | Regulation of neuronal synaptic plasticity | 69 | 1 | Arc | 0.0198 |
| 0045685 | Regulation of glial cell differentiation | 86 | 1 | Opalin | 0.0246 |
| 0032869 | Cellular response to insulin stimulus | 87 | 1 | Gh | 0.0249 |
| 0046889 | Positive regulation of lipid biosynthetic process | 94 | 1 | Gh | 0.0269 |
| 0060998 | Regulation of dendritic spine development | 97 | 1 | Arc | 0.0277 |
| 0032414 | Positive regulation of ion transmembrane transporter activity | 114 | 1 | Arc | 0.0325 |
| 0051260 | Protein homooligomerization | 116 | 1 | Arc | 0.0331 |
| 0071375 | Cellular response to peptide hormone stimulus | 119 | 1 | Gh | 0.0340 |
| 0006575 | Cellular modified amino acid metabolic process | 138 | 1 | Hmgn5 | 0.0393 |
| 0014013 | Regulation of gliogenesis | 148 | 1 | Opalin | 0.0421 |
| 1901564 | Organonitrogen compound metabolic process | 1208 | 2 | Hmgn5, Lars2 | 0.0423 |
| 0010469 | Regulation of receptor activity | 156 | 1 | Arc | 0.0443 |
| 0009952 | Anterior/posterior pattern specification | 170 | 1 | Arc | 0.0482 |
| 0043604 | Amide biosynthetic process | 214 | 1 | Lars2 | 0.0604 |
| 0043933 | Macromolecular complex subunit organization | 1504 | 2 | Arc, Hmgn5 | 0.0633 |
| 1901215 | Negative regulation of neuron death | 244 | 1 | Gh | 0.0686 |
| 0032412 | Regulation of ion transmembrane transporter activity | 249 | 1 | Arc | 0.0700 |
| 0006790 | Sulfur compound metabolic process | 271 | 1 | Hmgn5 | 0.0760 |
| 0009416 | Response to light stimulus | 288 | 1 | Gh | 0.0806 |
| 0050890 | Cognition | 325 | 1 | Arc | 0.0905 |
| 0010769 | Regulation of cell morphogenesis involved in differentiation | 344 | 1 | Arc | 0.0956 |
| 0007005 | Mitochondrion organization | 345 | 1 | Lars2 | 0.0959 |
| 0071417 | 9 Cellular response to organonitrogen compound |
347 | 1 | Gh | 0.0964 |