Table 2.
Phenothiazine C. neoformans SAR
| Compound | n | C. neoformans MIC (μg/mL) | ClogP | CNS MPO Score |
|---|---|---|---|---|
| 14a | 1 | 32 | 5.15 | 2.71 |
| 14b | 2 | 32 | 5.21 | 2.56 |
| 14c | 3 | 16 | 5.73 | 2.18 |
| 14d | 4 | 8 | 6.18 | 1.89 |
| 14e | 5 | 8 | 6.62 | 1.59 |
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