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. 2022 Apr 10;6:100013. doi: 10.1016/j.immuno.2022.100013

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© 2022 The Author(s)

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig 2 — Analysis of macrophages for different conditions of COVID-19 patients. A. The clusters of macrophages are colored according to the COVID-19 condition. B. The macrophages are clustered into five groups. For example, cluster #0 mainly consists of cells from the healthy condition, clusters #2 and #3 of cells from the severe condition, and cluster #1 of cells from the moderate condition. C. The joint density of DE genes in macrophages from three COVID-19 conditions (healthy group on the right, moderate group in the middle, and severe group on the left). D. Dot plot showing the expression level of genes in each cluster. E. GSEA analysis of DE genes for cluster #3 (left and middle) and cluster #1 (right).