TABLE 1.

Quality control MIC ranges of antifungal agents

Organism	Antifungal agent	MIC range (μg/ml)
		Present study	Reference rangeb
C. krusei (ATCC 6258)	Voriconazole	0.25–0.5	NA
	Itraconazole	0.25–0.5	0.125–0.5
	Amphotericin B	0.25–0.5a	0.5–2
P. variotii (ATCC 22319)	Voriconazole	2–8	NA
	Itraconazole	0.06–0.5	0.03–1
	Amphotericin B	0.125–0.05a	0.25–1

^aFor amphotericin B, Antibiotic Medium 3 was used rather than RPMI 1640. This medium is expected to result in lower MICs. 

^bThe reference MIC ranges for C. krusei were obtained from NCCLS document M27-A (10). MIC ranges for P. variotii were obtained from a published collaborative study (4). NA, not available.