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. 2022 Apr 10;103(7):1448–1465.e6. doi: 10.1016/j.apmr.2022.03.011
GRADE factors
Number of participants Number of studies Number of cohorts Univariate Phase Study limitations Inconsistency Indirectness Imprecision Publication bias Moderate/large effect size Dose effect Overall quality
Potential outcomes identified + 0 -
Lockdown
 MET-minute per week 2,617 3 3 3 1 X X X X +
 Duration of PA 6,118 3 3 3 1 X X X X +
 Duration of light PA 2,338 1 1 1 1 X N/A X X +
 Duration of MVPA 12,420 2 2 1 1 1 X X X X X X +
 Proportion of participants reported changes in PA levels 16,014 8 8 N/A 1 X X X X N/A N/A -
 Changes in number of participants involving in different PA categories 4,392 3 3 N/A 1 X X X X N/A N/A +
 IPAQ scores 1,047 1 1 1 1 X N/A X X X +
 Step counts (per day or per week) 748,971 4 4 4 1 X X +++
 Proportion of participants reported changes in exercise duration 2,640 2 2 N/A 1 X X N/A N/A ++
 Proportion of participants reported doing regular exercise 3,654 2 2 1 1 1 X X X X N/A N/A +/-
 Duration of sedentary time 11,333 3 3 3 1 X X X +
 Proportion of participants reported changes in sedentary time 6,045 4 4 N/A 1 X X X ++
No lockdown
 Proportion of participants reported changes in PA 5,599 1 1 N/A 1 N/A X X X X +
 Proportion of participants reported changes in exercise duration 5,599 1 1 N/A 1 N/A X X X X +
 Proportion of participants reported changes in sedentary time 5,599 1 1 N/A 1 N/A X X X X +

IPAQ = International Physical Activity Questionnaire; MET-min = metabolic equivalent-minute; MVPA = moderate-to-vigorous physical activity; PA = physical activities

Phase, phase of investigation. For univariate analysis: +, number of significant effects with a positive value; 0, number of non-significant effects; -, number of significant effects with a negative value. For GRADE factors: ✓, no serious limitations; ✕, serious limitations (or not present for moderate/large effect size, dose effect); ?, unable to rate item based on available information; N/A, not applicable. For overall quality of evidence: -, inconsistent; +, very low; ++, low; +++, moderate; ++++, high

PA = physical activities; MVPA = moderate-to-vigorous physical activity

Phase, phase of investigation. For univariate analysis: +, number of significant effects with a positive value; 0, number of non-significant effects; -, number of significant effects with a negative value. For GRADE factors: ✓, no serious limitations; ✕, serious limitations (or not present for moderate/large effect size, dose effect); ?, unable to rate item based on available information; N/A, not applicable. For overall quality of evidence: +, very low; ++, low; +++, moderate; ++++, high