Table 1.

Testosterone Products Approved by the Food and Drug Administration in Unites States (2021)

Delivery System/Drug	Brand Name	Recommended Dose Regimen	Available Format
Topical/Transdermal
Testosterone patch	Androderm	2 or 4 mg patch/day	4 mg starting dose, should not apply the patch to the same are within 7 days applied to back, abdomen, upper arms
Testosterone gel	AndroGel	1% gel – 50 to 100 mg of testosterone per day	25 or 50 mg testosterone packets
		1.62 % gel – 40.5 to 81 mg of testosterone per day	20.25 mg testosterone one pump actuation or a 20.25 mg packet. 40.5mg testosterone two pump actuation or a 40.5 packet Applied to shoulders and upper arms
Testosterone gel	Testim	1% gel – 50mg of testosterone /tube	50 mg /day starting dose Applied to shoulder and upper arms
Testosterone gel	Fortesta	2% gel 10mg/0.5 g per pump actuation	40 mg (4 pump actuations)/day starting dose Applied to inner thighs
Testosterone gel	Vogelxo	1% gel 50 or 100mg per tube or packet, 12.5mg per actuation for pump	Generic testosterone gel
	Testosterone Gel	1.62% gel similar to AndroGel (1.62%)	Generic, same as AndroGel 1.62%
Testosterone lotion	Axiron	2% lotion 30 mg/pump actuation	Start with 60 mg Applied to axilla Discontinued
Buccal/Nasal
Buccal tablets	Striant	30 mg twice/day	Applied to gum, dislodging of tablets Discontinued
Nasal gel	Natesto	11 mg gel intranasal three times per day	Start with 1 actuation (5.5 mg) one into each nostril total 11mg Apply to nose three times per day.
Oral Capsule
Testosterone undecanoate	Andriol	40 mg capsules two or three times a day	80 to 120 mg per dayNot available in US
Testosterone undecanoate	Jatanzo	158 to 396 mg twice per day	Start with 237mg twice a day with food.
Testosterone undecanoate	Tlando	225 mg twice per day	Tentative approval by FDA
Injection
Testosterone enanthate	Xyosted	50, 75 and 100mg in 0.5mL sesame oil	Autoinjector Start with 75 mg once per week subcutaneously injection to abdomen
	Delatestryl	200mg/mL sesame oil	Intramuscular injection once in 2 weeks Not available in US
Testosterone cypionate	Depo-Testosterone	100 mg/mL or 200 mg/mL in cottonseed oil	Administered by deep intramuscular injection to gluteal muscle once in 2 weeks. Can be administered subcutaneously every week
Testosterone undecanoate	Aveed	750 mg/3mL (250 mg/mL) in castor oil	Start with 750 mg, repeat 750 mg after 4 weeks and then every 10 weeks. Deep IM slowly into gluteal muscle. 30 minutes observation for pulmonary oil embolism, most last for few minutes to some several hours.
Implants
Testosterone	Testopel pellets	75 mg per pellet	Inserted subcutaneously by health professional in fat in hip area Implant 2 to 6 implants will last 3 to 4 months; 6 to 10 implants will last for 4 to 6 months