Table 1.
Demographics and clinical characteristics for all patients with Gleason Grade Group (GG) 1 on biopsy and subgroups based on Radical Prostatectomy outcome
| Radical-prostatectomy group | Biopsy GG1 | |||
|---|---|---|---|---|
| All | Confirmed GG1 | Upgrade to GG2 | Upgrade to > GG2 | |
| Number of patients, N | 111 | 49 | 47 | 15 |
| Age (at diagnosis), median (IQR) | 60.0 (57.0–65.0) | 58.0 (56.0–63.0) | 60.0 (56.0–65.0) | 60.0 (58.0–69.5) |
| PSA (ng/mL), median (IQR) | 5.35 (4.3–6.5) | 5.4 (4.3–6.4) | 5.1 (4.3–6.9) | 5.2 (4.5–6.6) |
| African American, n (%) | 8 (7.2%) | 4 (8.2%) | 3 (6.4%) | 1 (6.7%) |
| Positive family history, n (%) | 35 (31.5%) | 19 (38.8%) | 12 (25.5%) | 4 (26.7%) |
| EPI Score, median (IQR) | 32.4 (20.6–55.2) | 31.7 (20.7–45.0) | 28.8 (19.5–55.7) | 62.2 (49.3–66.8) |
| Radical-prostatectomy outcome, n (%) | ||||
| GG1 | 49 (44.1%) | 49 (100.0%) | – | – |
| GG2 | 47 (42.3%) | – | 47 (100.0%) | – |
| GG3 | 12 (10.8%) | – | – | 12 (80.0%) |
| GG4 | 1 (0.9%) | – | – | 1 (6.7%) |
| GG5 | 2 (1.8%) | – | – | 2 (13.3%) |