Table 2.

Alternative EPI cut-points for use in the Bx-GG1 population, for predicting ≥ GG3 pathology at RP

Cut point	10	15.6	20	30	40	50
N	111	111	111	111	111	111
Sensitivity	100% (78–nan)	100% (78.2–nan)	93% (68–100)	93% (68–100)	87% (60–98)	73% (45–92)
Specificity	4% (1–10)	18% (11–27)	24% (16–34)	53% (43–63)	68% (57–77)	78% (69–86)
NPV	100% (40–nan)	100% (81–nan)	96% (79–100)	98% (90–100)	97% (90–100)	95% (88–99)
PPV	14% (8–22)	16% (9–25)	16% (9–26)	24% (14–37)	30% (17–45)	34% (19–53)
Diagnostic odds ratio	inf	inf	4.4	15.9	13.6	9.8
Samples below cut point	4% (1–9)	15% (9–23)	22% (14%–30%)	47% (37–57)	60% (51–70)	71% (62–79)