Table 5.

Estimated marginal utilities (expressed as a disutility) for differences in attribute levels

		Disutility	95% CI
			Lower bound	Upper bound
Motor function
Can sit, stand and walk independently (>10 m)
Can sit, stand and walk with assistance		− 0.068	− 0.083	− 0.053
Can sit but cannot stand		− 0.222	− 0.242	− 0.201
Cannot sit		− 0.408	− 0.440	− 0.377
Breathing function
Can breathe without mechanical support
Mechanical support for some of the day (<16 h)		− 0.159	− 0.174	− 0.143
Mechanical support for >16 h of the day		− 0.304	− 0.328	− 0.281
Treatment administration
Oral liquid taken once daily at home
Injection into spine in hospital every 4 months		− 0.071	− 0.085	− 0.057
Treatment reaction
No treatment reactions
Reaction for 12 h every 4 months		− 0.057	− 0.071	− 0.042
Reaction for 1–2 days every 4 months		− 0.060	− 0.078	− 0.042
Reaction for 3–4 days every 4 months		− 0.087	− 0.103	− 0.071
Eyesight monitoring
No eye monitoring required
Monitoring if symptoms present		− 0.024	− 0.036	− 0.012
Monitoring twice a year for the first 2 years		− 0.023	− 0.037	− 0.009
Need for contraception
No requirement to use contraception
Must agree to use effective contraception		− 0.012	− 0.021	− 0.002

CI confidence interval; h, hours; m, meters