Table 4.

Results of a clustered conditional logit model of patient and caregiver preferences: subgroup who correctly answered at least three out of four comprehension questions

Attributes and levels	Coeff.	Robust std error	z	p value	95% CI (coefficients)		Odds ratios	95% CI (odds ratios)
Alternative-specific constant—reference category: Treatment A (left column)
Treatment A (left column)	0.018	0.109	0.170	0.868	−0.196	0.233	1.018	0.822	1.262
Motor function—reference category: worse by one level
Stable	1.837	0.220	8.360	0.000	1.406	2.267	6.277	4.081	9.655
Improved by one level	2.458	0.281	8.750	0.000	1.907	3.009	11.685	6.736	20.271
Breathing function—reference category: worse
Stable	1.790	0.228	7.870	0.000	1.344	2.236	5.987	3.833	9.352
Better	2.139	0.308	6.950	0.000	1.535	2.742	8.489	4.643	15.523
Treatment administration—reference category: oral liquid taken once daily at home
Injection in spine in hospital every 4 months	−0.814	0.157	−5.200	0.000	−1.121	−0.507	0.443	0.326	0.602
One-off injection in hospital with daily oral tablets for 2 months	−0.339	0.134	−2.520	0.012	−0.602	−0.076	0.713	0.548	0.927
Risk and side effects—reference category: 17% risk of diarrhoea and rash
Fever, headache, vomiting, body pain every 4 months	0.089	0.131	0.680	0.498	−0.168	0.346	1.093	0.845	1.413
10% risk of liver injury. Fatigue, headache, nausea for 2 months	−0.519	0.189	−2.740	0.006	−0.890	−0.148	0.595	0.411	0.863
Treatment evidence—reference category: demonstrated in Types 1, 2 & 3 SMA
Demonstrated in Types 1 and 2 SMA	−0.268	0.148	−1.820	0.069	−0.558	0.021	0.765	0.573	1.021
Demonstrated in Type 1 SMA	−0.783	0.222	−3.520	0.000	−1.218	−0.347	0.457	0.296	0.707

Model statistics: Wald χ² = 273.96; p < 0.001

Bold indicates statistically significant at 0.05 level

CI confidence interval, SMA spinal muscular atrophy