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. 2022 Apr 9;12:6012. doi: 10.1038/s41598-022-10059-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Barplot of Linear discriminant analysis (LDA) effect size (LEfSe). Horizontal bars represent the effect size for each taxon. The length of the bar represents the LDA score. LDA threshold score for discriminative features was set to 3.0. Dietary treatments: Control = control diet; CH = Chlorella vulgaris diet; CH + R = C. vulgaris diet supplemented with Rovabio® Excel AP; CH + M = C. vulgaris diet supplemented with a pre-selected enzymatic mixture.