Table 5.

DESeq2 output and contrast.

Contrast	ASVsa	baseMeanb	log2FC	lfcSEc	P-value	Genus
CH + R vs. control	ASV537	6.84	5.69	1.34	0.00	Rhodopseudomonas
	ASV688	3.94	5.23	1.48	0.00	Prosthecomicrobium
	ASV149	90.0	2.13	0.54	0.00	Colidextribacter
	ASV8	1515	1.04	0.34	0.00	Lactobacillus
	ASV191	251	− 2.30	0.63	0.00	Ruminococcus
	ASV25	2136	− 2.65	0.76	0.00	Treponema
	ASV124	102	− 3.46	0.66	0.00	Helicobacter
	ASV446	14.7	− 4.46	1.51	0.00	Asteroleplasma
CH + M vs. control	ASV4	1631	6.87	1.44	0.00	Escherichia/Shigella
	ASV23	2322	2.04	0.66	0.00	Alloprevotella
	ASV108	330	1.86	0.63	0.00	Sutterella
	ASV149	90.0	1.75	0.53	0.00	Colidextribacter
	ASV199	51.6	− 1.26	0.42	0.00	Solobacterium
	ASV151	60.8	− 2.91	0.63	0.00	Catenibacterium
	ASV99	108	− 3.61	1.26	0.00	Streptococcus
	ASV446	14.7	− 4.48	1.48	0.00	Asteroleplasma
	ASV239	68.2	− 4.67	1.36	0.00	Mitsuokella
CH vs. control	ASV8	1515	1.17	0.34	0.00	Lactobacillus
	ASV108	330	2.56	0.64	0.00	Sutterella
	ASV149	90.0	2.06	0.54	0.00	Colidextribacter
	ASV537	6.84	6.50	1.33	0.00	Rhodopseudomonas
	ASV688	3.94	5.17	1.48	0.00	Prosthecomicrobium
CH vs. CH + R	ASV124	102	3.72	0.68	0.00	Helicobacter
CH + M vs. CH + R	ASV4	1631	− 7.67	1.48	0.00	Escherichia/Shigella
All (CH, CH + R, CH + M) vs. control	ASV8	1515	1.04	0.34	0.00	Lactobacillus
	ASV25	2136	− 2.65	0.76	0.00	Treponema
	ASV124	102	− 3.46	0.66	0.00	Helicobacter
	ASV149	90.0	2.13	0.54	0.00	Colidextribacter
	ASV191	251	− 2.30	0.63	0.00	Ruminococcus
	ASV446	14.7	− 4.46	1.51	0.00	Asteroleplasma
	ASV537	6.84	5.69	1.34	0.00	Rhodopseudomonas
	ASV688	3.94	5.23	1.48	0.00	Prosthecomicrobium

Control = control diet; CH = Chlorella vulgaris diet; CH + R = C. vulgaris diet supplemented with Rovabio® Excel AP; CH + M = C. vulgaris diet supplemented with a pre-selected enzymatic mixture.

^aASVs: abundant amplicon sequence variants.

^bbaseMean: mean of normalized counts of all samples.

^clfcSE: standard error estimated for the log2 fold change.