Fig. 2.

Inhibition of hsa_circ_0001944 decreased cell proliferation, reduced the migrated and invaded cells, but induced the cell apoptosis. A Verification of the transfection. B, C Cell proliferation was evaluated in LoVo and SW620 cells transfected with hsa_circ_0001944 siRNA (si-circ_0001944), using the negative siRNA as reference. D Quantitative statistical chart of the apoptotic cells. E, F Numbers of migrating cells were determined using Transwell assay. G, H Numbers of invading cells were determined using Matrigel-modified Transwell assay. Student t-test was applied. Error bars are mean ± standard error from three replicate samples. *P < 0.05, **P < 0.01***P < 0.001