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. 2022 Apr 9;13:23. doi: 10.1007/s12672-022-00485-2

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — miRNA-548b-3p knockdown deteriorated hsa_circ_0001944-caused proliferation inhibition, migration inhibition, invasion inhibition, and apoptosis induction. A The transfection efficiency was determined by qRT-PCR. B Cell proliferation was evaluated by XTT assay. C Quantitative statistical chart of the apoptotic cells. D, E Numbers of migrating and invaded cells were determined using Transwell assay. *P < 0.05, **P < 0.01, ***P < 0.001 (vs si-ctr). ^&P < 0.05, ^&&&P < 0.001(vs si-ctr + anti-ctr)