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. Author manuscript; available in PMC: 2022 Apr 10.
Published in final edited form as: Sci Transl Med. 2021 Jan 20;13(577):eaba7401. doi: 10.1126/scitranslmed.aba7401

Figure 4. LY2606368 abrogates cell cycle checkpoint signaling in MB cells and alters cell cycle arrest following treatment with DNA-damaging chemotherapy.

Figure 4.

(A, B) D425 cells were treated with the indicated agents (A) or D283 and D425 cells were treated with the indicated agents (B). Cells were examined using flow cytometry for cell cycle phase or apoptosis. Data are mean ± SD from three independent experiments. Significance was determined using unpaired t tests. P < 0.05, *; P < 0.01, **; P < 0.001, ***; P < 0.0001, ****.