Table 1.
Comparison of Total Metabolite Values in METH Users and the Healthy Control Group
| Metabolites (ppm, Mean ± SD) | METH Users (n = 42) | Healthy Controls (n = 21) | Sig. |
|---|---|---|---|
| Dopamine | 4.21±1.25 | 2.38±0.8 | <0.001* |
| Serotonin | 3.75±1.38 | 1.9±0.69 | <0.001* |
| NAA | 22.24±5.6 | 26.14±4.6 | 0.008 * |
| Cre | 12.02±3.1 | 7.78±1.4 | <0.001* |
| Cho | 9.6±3.2 | 9.7±2.11 | 0.89 |
| Glx | 2.5±1.43 | 4.6±1.1 | <0.001* |
| MI | 2.59±1.33 | 4.9±1.29 | <0.001* |
*
Significantly different from controls, Abbreviations: METH, Methamphetamine; ppm, parts per million; NAA, N-acetyl aspartate; Cho, Choline; Cre, Creatine; Ml, Myo-inositol; Glx, Glutamine plus Glutamate; PANSS; Positive and Negative Syndrome Scale.